Smart Data Analysis and Statistics

Smart Data Analysis and Statistics B.V. is at the forefront of biostatistical innovation, expertly converting real-world data into compelling evidence compliant with Health Technology Assessment (HTA) standards. Our commitment to cutting-edge analysis methodologies ensures that our clients are equipped with advanced, scalable solutions that meet the rigorous demands of the healthcare industry.

Analysis of Clinical Trials

Development of Statistical Analysis plan
Development of mock TLF
Experience with Phase I, Phase II, Phase III, Phase IV trials
QC of ADAM datasets
Preparation of tables, figures and listings using R or SAS
Experience in generalized linear (mixed) models, survival analysis, hypothesis testing, sample size calculations
Preparation of ToC, TLF, ADAM specifications
Integrated Summary of Safety analyses
Trainings and workshops

Analysis of Real-World Data

Analysis of drug safety and effectiveness
Incorporation of historical controls
Estimation of prevalence, incidence and disease progression
Analysis of healthcare utilization and costs
Trainings and workshops

Evidence Synthesis

Meta-analysis of clinical trials
Indirect Treatment Comparisons, e.g. using network meta-analysis, MAIC, or STC
Support of aggregate safety reviews
Trainings and workshops

Research & Innovation

Participation as industry partner in academic research projects (e.g. EU doctoral networks)
Collaboration with the Utrecht University, the University of Copenhagen, the National Institute for Health and Care Excellence, and other institutions in applied and methodological research
Training and supervision of PhD students

Talent Access

Providing freelance or interim specialists in biostatistics, data science, and statistical programming
Connect with an international pool of scientists specialized in biostatistics and epidemiology Software Development

Software Development

Development & maintenance of R packages
Development, maintenance and hosting of Shiny apps
Automation of conduct and reporting of statistical analyses

Read our story in making precmed

An R Library to help researchers with the implementation of precision medicine in R

Find out more about our scientific impact

4

Published Books

Discover Expertise: Explore our Published Books section for concise, authoritative works embodying our commitment to science and academia.

117

Research Publications

Explore Our Insights: Uncover a wealth of knowledge from our scientific publications, showcasing our contributions to diverse journals across a spectrum of industries